Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. The most serious side effects are severe breathing problems like slow and shallow breathing, which may even lead to stopping breathing or inability to breathe. In case you experience any of the above mentioned side effects, stop taking ZALVISO® and tell your doctor or nurse immediately.

Very common side effects (may affect more than 1 in 10 people) nausea, vomiting, fever.
Common side effects (may affect up to 1 in 10 people) confusion, dizziness, headache, drowsiness, increased heart rate, high blood pressure, low blood pressure, constipation, indigestion, itching of the skin, involuntary muscle cramps, muscle twitching, difficulty passing urine.
Uncommon side effects (may affect up to 1 in 100 people) allergic reactions, lack of interest or emotion, nervousness, sleepiness, abnormal sensation of the skin, problems coordinating muscle movements, muscle contractions, exaggeration of reflexes, vision disturbances, decreased heart rate, dry mouth, excessive sweating, rash, dry skin, chills, weakness.
Frequency not known (frequency cannot be estimated from the available data) severe allergic reactions (anaphylactic shock), convulsion (fits), coma, small pupil size, redness of the skin, withdrawal syndrome.

Reporting of side effects

If you get any side effects, talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system and on the Grünenthal website

By reporting side effects, you can help provide more information on the safety of this medicine.

Read all of the ZALVISO® Package Leaflet carefully before you start taking ZALVISO® because it contains important information for you. If you have any further questions, ask your doctor or nurse. If you get any side effects, talk to your doctor or nurse.

For additional information, please download the entire Package Leaflet.